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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8413e6893d099c865f94f2908d616a00c6d1c15f3b5ef14dc27803ba4cb534' 
  AND token = 'smN67eATg1okGq0twOKsNIb21FauG2LZR/T294aP738=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}