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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ef74d3695e8cbc8088d6b3005dc11d3bc8c26ccd9d78f6a4bc0044efcd9301' 
  AND token = '2bz4akl+uRhnETpOfNME8i7LHEcHJVwJ7s1bV44EtME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}