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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e197b50037f9bdc24492b9b64241cdf71c8a15574ed35429684773ab4ed33d45' 
  AND token = '792/2/CIEbk76JscETIxLk++p7Ty6NJjZZcw5kUQKZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}