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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a01413de8c65895c1f00cf0ae79a6a43ffdf310ec47392af069b2449edc3873' 
  AND token = 'roagGOpX4Gn2Fy0LzLknh+nD0RdiV1/lzmoKvi0vhvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}