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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edbe734994767fdfb8036ffcda1d53bc28fc9f32d83fe5945418c14341cf3757' 
  AND token = 'Ny2ZybodlNvuFpxxrYx9+MrKdt6Ym9ZpdG2oShZMWzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}