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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81524f16812e58023f16017cf681747363ac85660d1b86d6ba6efe322440191' 
  AND token = 'rPv0u0SNBishL3O0OkopcosmFT1GgbvAm4/hccIbAVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}