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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd459877bfe948d3c1c53c4c4636d63d40e609d64e5fad1bed00321a994e15792' 
  AND token = 'vCBmTma9wDA60C8pUt6J+mP33q/lelnKxnqjvOX09iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}