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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd81c3e5e8a855ea5e06b000e38f9a8633e421336c9d6632167ac97c6b6e346' 
  AND token = 'RiHxunOyo0OhWgaYuQVAmaEF8FlLwS2JWwlEJ4U8J/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}