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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1e8b71ac3d7cc7b658eb0e6327c94edd1db738beef25b29e7e0eb6818fb09b' 
  AND token = 'WfEUV1upyFeLTY8B+6gpOgs7MOmxz1HecNV23fXMad0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}