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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6b829d0f3a1e90777e45b5628df42f96eb930a34e6a7a83c6a7b452affa756' 
  AND token = 'VFZA3knUIJHkCgWRLetvZAFhXgoO3jPUnaAGubdte34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}