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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259e42ee9e69e5c1c6dc3865d77d0fe41fa67a4b3050e64cff58f5b6543132f3' 
  AND token = 'khGxdf1PbPTrlvB8VIO5fxYLhLN034hWkfMq0mpem9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}