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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca4ac00bca2c48bb213fb500b790bb551f15aa6ae60acb5cc192939320c9bb9' 
  AND token = '3wi1mQ2ZPQLOjN7eZRfhszDG4bS+quKlzEU+sRqvB0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}