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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337723b6b4e5ff5fa511f10ee260f5fd4bf69af00144d19c39b34976ee121652' 
  AND token = '3Crib4OPoM/HBefOkUe16itsMcr1YawTowcgJTgCw7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}