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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4fd65d63907c1a65a50d4a446dd9c5c424858fe13509c608154bc37dda2f01c' 
  AND token = 'G4ILvjYdChvYpNYAc1TObS11JqrhxRHJUoFtNAte2Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}