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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43df2c31cf7e26abbaadf3a5bae62948cf827a537e5089e6f8edc0a549580e07' 
  AND token = 'hm7Py8qGzNe4V4q4tYqRCIhQEWnbqhT/wyjxx/dhtw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}