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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4dc8f282bc5e99643e2c6b4ce469fbf297362cf0876fdc1f9b92ff03c8e4bf' 
  AND token = 'EFebp5FLloIDYsACU7DP1GFQKuiB3kTgnZ3ZMzWT/1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}