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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cab5084f2c68fe17178ae409f71205f54d4b4b2c170ed815d8ebd3acffe0cb' 
  AND token = 'THx4qIokw25dYjNgKZKzIXHZXzORXI5NX3R9Xk5UpKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}