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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c05813400216a46cbeec0d8afb1f8f9d856102c55877508c977a93fec5e0f7e' 
  AND token = 'lPLePXxWI4KAvxxC2JZtxAIQSKpBa9axA2xae8WxlE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}