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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2422910a0e23f1dfbc16f0a725d4bf96ae3e21242daecc97ce23e4423de1dc55' 
  AND token = '3MKs/csuzDULNeuH3Mm9DMZWkbehZmvVf7pD4xe9I80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}