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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca72e6d89215a63ec310a4c2dbad62c35815e291fb64eac217f65ddc5533364' 
  AND token = 'YRKLu/P3r5/zyZIcLOa6fN0R2r71gy0u+B6XVhhqvc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}