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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e9988f87706a0dfebf304b39950f1f0b47fe153b2689ff2d7769e2fcd902b3' 
  AND token = 'E1AgyO8UBTPgpxpFmUUeUR214SwRuFbNG/5QIG2ZA24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}