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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6903c410f97f0a6fd6a6ab2ae13eff6b6738e3ba994e4ea8351b6766baac235a' 
  AND token = 's4YX6WN9oerjgrKYMtSCULosnAFtossHOW8x99zWid8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}