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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d2ea635dcf631a9eabe43dc0f3c6d56b6a98c2621c2c61cfeea1f341c74181' 
  AND token = 'gJuXp6zffs6flStXdnDVYgl/dVg7PKrFPmR0x0F/jgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}