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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10b2589ad640c94c66e5f1b55a06a1de5d18cd08fc99b94344669f6c2d2a364' 
  AND token = 'VpZJ0cby5aIXRPuPQ7DT7vuIwMLn+TcsGujmGy1cQYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}