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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04350e724edb4dd5738a338a26edab022a4c896f0809ce8291a80c6596c0f22f' 
  AND token = 'jm861/ke9xW+EZ8pPaNgTY8atVe0Hom75z/wGpPGlcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}