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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953195bc4996d4edf95f06137280ba064fe33b280ec7215746005ba03db77038' 
  AND token = 'vJ6Scz64mDh8Wzpk6RY6NoothETZ+DaJrEcr2Nq5rGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}