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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7119306335d13b96733b3ebb9dced507d5279cf13d88c4d7ffc8dbce9eb639a' 
  AND token = 'jPKW7ENJRqizsyVjy/Exyi+2uGya8uh/y7HDlQ4nVKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}