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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aaf754c63f546e28e30c9afde90bce28ad10ce8b3d29a32fab1df9571c271cf' 
  AND token = 'l5wVG/FWEdxrID8mDg7U/KUlVE4n3Zx1YNaRLpeGrlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}