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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891c91b727e949b4655974b5fd0ea3758a48edef3f58025fb97a6faea773a033' 
  AND token = 'osy4NcC8K0UH0zaVQR2kWj5qRR9omfU+mmE500TH9wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}