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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c195e043e420c2d84763aa70d3b4084fd3ed88152eff7f0cc5267270cb6775b9' 
  AND token = 'x5WbWnmoJhhh/MIwt4FMr/65dloNQ1ik6rcV7pNkae0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}