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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b06a390a8962c07279425561508824b80c0b2cb8a8ef817b00be1ab868b8303' 
  AND token = '1rz6gCdOJb7GrCrl4E3sHTl448wU5hEUw+zEvjW00Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}