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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad17e5ac7c43eec45509051a5fb5ee17044b68361e301e10902bd9abbe708b1' 
  AND token = 'IjP2Ix942pdbUxyuEIE3q+CC7DaFxUl0P8AQg4CwHfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}