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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5dc65106f18c52efe65b95dc54b2e33bb28e277731b7bd7076f1ee66353ae61' 
  AND token = 'C5O6qQRkXhXC0eNAsA1W4u9xyymM5iEVZ5xyT+RW61A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}