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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e73cfa8fad1169763088525a9a81b54f2b984cd67678b814127a6807b5410c68' 
  AND token = '+RNPSv9xpSXaaiDlnLHNzlbVqVNNhtxsubWxcP/QyKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}