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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5211324922ecd978bcb6dd1572299e12f7803c91f481734f0d7b8a519f3a899' 
  AND token = 'pR3EPSIFWSf3K2ao50gfPmHLbeSLbMgGdbr+c8rJSrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}