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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f26a7ee8d6352d89352ffd68a1b88756b5dce98e34ee96702cb51f7e5f1c0b' 
  AND token = 'UV2b8KNrK0lS3kov7BUJb5qi0/auiDNDObXNSdk37WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}