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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05814fe0aa5d5c04821a3db3e741d4867a86e13bcccf64bd20f34e2fa3e94ad4' 
  AND token = 'mGXD/kJ26fQIWTCJYTgHbGRQ1x2sas+FknaIQGAwsaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}