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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c535325521c758578d7309c0ddaa00a92fbdb4b28531a021a7cc5447a9d1b03' 
  AND token = 'Zm6npz3gF9PMiyCCJT8658flD54iAT+kPKyvVZjcRIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}