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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4545eb5632b610e7e3c5a90fb5652108e08100c6f8937e9227dfcc1f3a3409c' 
  AND token = 'pyEbePHVZtcWxbfuguhpHW10B4nL6Wvnzh2eKSyV/3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}