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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82174c8429785605d82019e7612a9590863b949dc0b57a80b002bdddc17bdd0' 
  AND token = '8fy/dpQYsWJqtdBOZJ/Qjaz8zRwQfIZtVFgfi786lcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}