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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3da2c8257af55807c41c8380821dd81b2dcdb28a7899393376489db822b94c25' 
  AND token = 'cNjmu1/3ipJwTGx6hASeSTlO6igg5vatWm11fOSrTmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}