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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d66055f1caa7597e196a5bafe389e744467c4a5dc74e5ebf06d6bc332cbbd8f' 
  AND token = 'Ag6vV1MPMAPP+xA/1wIsusaBnX0G61dOO/V0kFk02Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}