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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c89fb8bf788fc5440a816ed73bee73b8288de7117f1f535f13071da141a035' 
  AND token = '9tiLklQSRJ5/ZUp4n/Y1m6SQPTXPcGihxkd30Edni7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}