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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a210f8dd50eb74ac32b1bd8028bfdcfe2688734316b14c9e7d16e30f2fab386f' 
  AND token = 'aKwkHAtHtVPjYh9JOEvcpXs2tprn3ag3E1XC/5jPjvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}