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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3373e5f77b9f363098405ec89d0d96f920e78446554ea2f5aa40285c7cf837d' 
  AND token = 'iyxPiTQFmRR9Hy6dELj2tTLKltNaeBLgEjUVJlTpeZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}