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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a956946e860af12a28d76e0b18c2311357f20f4bd0301f4e2ead55d2e353a99' 
  AND token = '9d+u2ZhvBJ4Sv+AD99grut1+xPd3nISnSEYy7VHsaxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}