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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8067b4eb464e9f9ffd29bb281da71dad0f86b95a38c99b00fa99d8756bf5917e' 
  AND token = 'u2C1ol0EqzvDUER1x4ZNFwHC81ovd+ZEFR6XeuXlVls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}