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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3234cc202591a252a07e71eefa4828c00d3e2f42acd255c4022ce1a1ab83665b' 
  AND token = 'Mn0tmRdO9GwiT3Ip6LsuI3o4SrTKXeIs+d8DFnrcI/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}