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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16be2626a877209a1c928cdda01c93a2fedfd18306a38e79075252e472f10ea4' 
  AND token = 'MIlGFxZT0plnIf/SgsWWawTR1oLuWRC+lmEZQGehizA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}