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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '367c773bc8f171a92b72ef2522ab19b9cfc84036b21494c95a106994055fa8cc' 
  AND token = '2ukTC9yGVcF+LN8Ah2BIpH3SAKQ6pxcCx4mCBB0MGic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}